Deployment
On Demand - All software is available via a hosted service.  This means no software installation and no requirements for local IT resources.
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Faster "Go Live"

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Eliminates need for additional hardware and supporting software requirements such as SQL Server, MS Office, etc.

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Any Time/Anywhere Access

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Virtually eliminates need for IT resources

 

On Premise - All software is installed at a location of your choice (your office, 3rd party data center, etc.). 

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Software installed within your environment

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Better suited for integration with local systems (phone integration, other applications)

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Control over deployment of updates, upgrades, functionality

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More Flexibility for customizations, modifications and workflow control

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Internal IT staff has final authority on level of access, design requirements, corporate computing standards

Access
Local Desktop/Network - software is available from the local computer's desktop. 
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Alleviates reliability on internet access and potential bandwidth or speed issues

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Tighter integration with local computer applications/files

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Potential for disconnected/remote environment

 
Remote Access - All software applications and files are available via a "virtual desktop" connection (ie Citrix or MS Terminal Services) over the web.
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All applications/data available from any computer (requires download of small applet/client file)

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Nominal computing power requirements on the local computer

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Any time/anywhere access

 
Web Client Access - Access to your system is achieved through a web portal access
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Requires no installation of software

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Available any time anywhere from any computer

 
Mobile - The system can be accessed using either a Smart Phone with Microsoft Windows Mobile or Blackberry Phone.
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Gain access to all infomration without the need for a computer

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Any time anywhere access (sync may be limited by available connection)

Method of Payment
Subscription - Pay a monthly fee on a per user basis
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No software purchase required

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Great for cash flow

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Easy to sign up and get going

 
Purchase - Buy the necessary software and labor services required for implementation
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No "never-ending" monthly payment to worry about

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Most economical choice in the long run (24-36 months)

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Great asset for company valuation

 
Lease/finance - Spread the purchase of software and labor over a period of time
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Little or no up front cash requirements

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All the benefits of a purchase without the negatives of the subscription (never ending payments)

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Once the final payment is made, you own it